Date: 07th April 2016
Do hotels.com accept Paypal as a payment option for hotel bookings and reservations with them? Yes, when checked during a visit to the site 07th December 2015, Hotels.com state that Paypal can be used on their site
Visit Hotels.com Ireland site
Visit Hotels.com UK site.
List of other sites that accept Paypal for hotel bookings
Most of Hotels.com are prepaid, and you are charged immediately at the time of booking with them. So you should make sure you have sufficient daily spending limits so your account will not be blocked. When checked in December 2015, Hotels.com allow online booking with MasterCard, Visa, American Express, Diners Club, Discover credit cards, Visa Electron, as well as PayPal